Differential microthermometry enables high-throughput calorimetry
Literature Information
Amin Kazemi, Mohammad Zargartalebi, David Sinton
The assessment of heat capacity, or calorimetry, is critical to the development of fluids that will cool electrified processes and systems, such as computing infrastructure, data centres, and high-performance electric vehicle batteries. However, the throughput of conventional measurement approaches is limited by the need to quantify heat flux. Here, we present an approach that is independent of heat flux quantification, eliminating the intrinsic bottleneck in calorimetry and enabling high-accuracy, high-speed fluid screening. The principle is the measurement of an advective temperature bias introduced by a sample fluid vs. a reference fluid, flowing in parallel symmetric microchannels. This microthermometric approach is tested in non-insulated flow-through microfluidic channels, demonstrating heat-flux independence while enabling continuous heat capacity measurement of a fluid stream. We assessed performance by measuring the heat capacity of 35 pure liquids and gases, liquid mixtures, and nanofluids, exhibiting a broad range of viscosities (0.015–400 mPa s), thermal conductivities (0.02–0.6 W m−1 K−1), temperatures (5–120 °C), and pressures (1–70 bar). We achieve an accuracy of ±1.1%, matching that of the gold standard, with a throughput that exceeds the incumbent by two orders of magnitude (∼1 min vs. hours). This approach enables continuous and rapid screening in a high-throughput manner, enabling the accelerated discovery of energy-carrying fluids.
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Energy & Environmental Science is an international journal dedicated to publishing exceptionally important and high quality, agenda-setting research tackling the key global and societal challenges of ensuring the provision of energy and protecting our environment for the future. The scope is intentionally broad and the journal recognises the complexity of issues and challenges relating to energy conversion and storage, alternative fuel technologies and environmental science. For work to be published it must be linked to the energy-environment nexus and be of significant general interest to our community-spanning readership. All scales of studies and analysis, from impactful fundamental advances, to interdisciplinary research across the (bio)chemical, (bio/geo)physical sciences and chemical engineering disciplines are welcomed. Topics include, but are not limited to, the following: Solar energy conversion and photovoltaics Solar fuels and artificial photosynthesis Fuel cells Hydrogen storage and (bio) hydrogen production Materials for energy systems Capture, storage and fate of CO2, including chemicals and fuels from CO2 Catalysis for a variety of feedstocks (for example, oil, gas, coal, biomass and synthesis gas) Biofuels and biorefineries Materials in extreme environments Environmental impacts of energy technologies Global atmospheric chemistry and climate change as related to energy systems Water-energy nexus Energy systems and networks Globally applicable principles of energy policy and techno-economics











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