Single atom nanozymes for bacterial infection therapy
Literature Information
Xing Lan, Miaomiao Chen, Xin He, Shutao Gao, Xinghua Zhao
Bacterial infection-related diseases continue to pose a significant challenge to global human health. Antibiotic therapy, as a conventional therapeutic strategy, has been extensively employed in clinical settings to treat bacterial infections. However, the effectiveness of these conventional strategies is often impeded by the antimicrobial resistance of bacteria. Consequently, the development of alternative antibacterial agents has emerged as a promising approach to addressing this issue. In recent years, single-atom nanozymes (SAzymes), a novel class of nanocatalytic medicines, have garnered increasing attention due to their numerous advantages, including uniformly dispersed metal active sites, tunable coordination structures, and maximal metal atomic utilization efficiency. To date, a variety of SAzymes have been developed and widely applied in antibacterial therapy. In this minireview, we provide an overview of the latest advances in the synthesis and antibacterial application of different metal-based SAzymes. Furthermore, we discuss the future challenges and opportunities of utilizing SAzymes for bacterial infection treatment. It is our hope that this minireview will contribute to the development of the next generation of SAzyme-based antibacterial agents.
Recommended Journals

Russian Chemical Bulletin

Chemistry Education Research and Practice

Journal of Peptide Science

Journal of Saudi Chemical Society

Russian Journal of Applied Chemistry

Crystallography Reports

Acta Materialia

Chemical Communications

Current Opinion in Colloid & Interface Science

Russian Journal of Bioorganic Chemistry
Related Literature
Efficient enantioselective synthesis of CF2H-containing dispiro[benzo[b]thiophene-oxindole-pyrrolidine]s via organocatalytic cycloaddition
Yabo Deng, Yongzhen Li, Yalan Wang, Shuo Sun, Sichao Ma, Pengfei Jia, Wenguang Li, Kairong Wang, Wenjin Yan
DOI: 10.1039/D1QO01392K
A desulphurization strategy for Sonogashira couplings by visible light/copper catalysis
Xuan Li, Xiaolong Zhu, Xiuyan Song, Qirong Deng, Jian Lv
DOI: 10.1039/D1QO01548F
Activation of disulfide bond cleavage triggered by hydrophobization and lipophilization of functionalized dihydroasparagusic acid
Fuyuhiko Inagaki, Miyuki Momose, Naoya Maruyama, Kenkyo Matsuura, Tsukasa Matsunaga, Chisato Mukai
DOI: 10.1039/C8OB01055B
Hydroxyl group-directed, tartaric acid-catalyzed synthesis of meta-functionalized aryl ethers and phenols through domino conjugate addition/aromatization of para-quinols
Guo-Shu Chen, Jia-Hui Li, Shu-Jie Chen, Wen-Xia Lin, Hai Ren, Dong-Sheng Deng, Yun-Lin Liu
DOI: 10.1039/D1QO01078F
Mild and efficient synthesis of indoles and isoquinolones via a nickel-catalyzed Larock-type heteroannulation reaction
Wei-Zhi Weng, Jian Xie, Bo Zhang
DOI: 10.1039/C8OB00795K
In situ phosphonium-containing Lewis base-catalyzed 1,6-cyanation reaction: a facile way to obtain α-diaryl and α-triaryl acetonitriles
Yuan Chen, Xiaoyu Ren, Yumeng Guo, Bing Yi, Hongkui Zhang, Guowei Gao, Tianli Wang
DOI: 10.1039/D1QO01501J
Rapid and reversible hydrazone bioconjugation in cells without the use of extraneous catalysts
Rahul Nisal, Gregor P. Jose, Chitra Shanbhag, Jeet Kalia
DOI: 10.1039/C8OB00946E
Highly regioselective, electrophile induced cyclizations of 2-(prop-1-ynyl)benzamides
Bhavani Shankar Chinta, Harikrishna Sanapa, Kamala Prasad Vasikarla, Beeraiah Baire
DOI: 10.1039/C8OB00434J
Water-promoted regio-selective trifluoromethylation of vinyl conjugated diazoacetates
Xinxin Han, Xin Liu, Yueyun Bao, Hunahuan Song, Yu-Rou Zhao, Xiaoying Wang, Junjie Zhang, Le Liu, Xin-Hua Duan, Jinbo Hu, Mingyou Hu
DOI: 10.1039/D1QO01654G
Rhodium(iii)-catalyzed annulation of 3-arylquinazolinones with alkynes via double C–H activation: an efficient route for quinolino[2,1-b]quinazolinones
Jian Huang, Wei Chen, Jiazhi Liang, Qin Yang, Zhihong Deng, Zhibin Song, Yiyuan Peng
DOI: 10.1039/D1QO01186C
You might also like
How should waste containing 4-Bromo-3-methyl-2-thiophenecarboxylic acid (CAS: 265652-39-9) be handled?
Waste containing 4-Bromo-3-methyl-2-thiophenecarboxylic acid (CAS: 265652-39-9) ...
What industries use (2S,5S,2'S,5'S)-1,1'-(1,2-Ethanediyl)bis(2,5-dimethylphospholane) (CAS: 136779-26-5)?
(2S,5S,2'S,5'S)-1,1'-(1,2-Ethanediyl)bis(2,5-dimethylphospholane) is primarily u...
What industries use Ethyl 2-(2-bromo-5-fluorophenyl)acetate (CAS: 1214910-61-8)?
Ethyl 2-(2-bromo-5-fluorophenyl)acetate (CAS: 1214910-61-8) is used in the pharm...
How is 4-Methyl-2-benzofuran-1,3-dione (CAS: 4792-30-7) typically synthesized?
4-Methyl-2-benzofuran-1,3-dione (CAS: 4792-30-7) can be synthesized through seve...
What industries use 4,6-Dichloroquinoline-3-carbonitrile (CAS: 936498-04-3)?
4,6-Dichloroquinoline-3-carbonitrile (CAS: 936498-04-3) is used in the pharmaceu...
What are the main uses of Chloro[tris(para-trifluoromethylphenyl)phosphine]gold(I) (CAS: 385815-83-8)?
Chloro[tris(para-trifluoromethylphenyl)phosphine]gold(I) is primarily used in or...
Is 2-Bromo-5-nitrofuran (CAS: 823-73-4) safe?
2-Bromo-5-nitrofuran (CAS: 823-73-4) is generally considered safe when handled w...
How should 5-Bromo-2,3,4-trifluorobenzoic acid (CAS: 212631-85-1) be stored?
5-Bromo-2,3,4-trifluorobenzoic acid should be stored in a cool, dry place away f...
What are the main uses of Zinc bis(aminoacetate) (CAS: 7214-08-6)?
Zinc bis(aminoacetate) (CAS: 7214-08-6) is primarily used in the pharmaceutical ...
How should Adamantan-1-ylmethanol (CAS: 770-71-8) be stored?
Adamantan-1-ylmethanol should be stored in a cool, dry, and well-ventilated plac...
Source Journal
Biomaterials Science

Biomaterials Science is an international high impact journal exploring the science of biomaterials and their translation towards clinical use. Its scope encompasses new concepts in biomaterials design, studies into the interaction of biomaterials with the body, and the use of materials to answer fundamental biological questions. Papers do not necessarily need to report a new biomaterial but should provide novel insight into the biological applications of the biomaterial. Articles that primarily focus on demonstrating novel materials chemistry and bring a molecular picture to bear on a given material’s suitability as a biomaterial are more suited to our companion journal, Journal of Materials Chemistry B. Biomaterials Science publishes primary research and review-type articles in the following areas: molecular design of biomaterials, including translation of emerging chemistries to biomaterials science of cells and materials at the nanoscale and microscale materials as model systems for stem cell and human biology materials for tissue engineering and regenerative medicine (Nano)materials and (nano)systems for therapeutic delivery interactions at the biointerface biologically inspired and biomimetic materials, including bio-inspired self-assembly systems and cell-inspired synthetic tools next-generation biomaterials tools and methods


![2,5-Furandione, dihydro-3-[3-(triethoxysilyl)propyl]- structure 2,5-Furandione, dihydro-3-[3-(triethoxysilyl)propyl]- structure](https://static.chemtradehub.com/structs/936/93642-68-3-3b4b.webp)

