Synthesis of photolabile protecting group (PPG) protected uronic acid building blocks: applications in carbohydrate synthesis with the assistance of a continuous flow photoreactor

Literature Information

Publication Date 2019-10-14
DOI 10.1039/C9QO01010F
Impact Factor 5.281
Authors

Varsha Tiwari, Adesh Kumar Singh, Priyanka Chaudhary, Peter H. Seeberger, Jeyakumar Kandasamy


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Abstract

Photolabile protecting group (PPG) protected uronic acid building blocks were prepared and used for carbohydrate synthesis. Deprotection of the photolabile protecting group was achieved very efficiently by employing a continuous flow photoreactor under neutral conditions. Many conventional protecting groups were found to be stable during the photo-cleavage of the 2-nitrobenzyl group at 355 nm in methanol.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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