Highly efficient copper-catalyzed direct C–H amidation of quinoxalin-2(1H)-ones with amidates under microwave irradiation

Literature Information

Publication Date 2019-02-12
DOI 10.1039/C9QO00063A
Impact Factor 5.281
Authors

Jinwei Yuan, Junliang Zhu, Junhao Fu, Liangru Yang, Yongmei Xiao, Pu Mao, Xue Du


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Abstract

A novel and highly efficient copper-catalyzed direct oxidative amidation of quinoxalin-2(1H)-ones with a variety of aromatic and aliphatic amides was described. This methodology provided a practical approach to various 3-acylamino quinoxalin-2(1H)-ones from readily available starting materials in good to excellent yields.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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