Cationic polycarbonates via ring-opening polymerization: design, synthesis, and applications

Literature Information

Publication Date 2018-11-12
DOI 10.1039/C8PY01365A
Impact Factor 5.582
Authors

Yu Dai, Xiaojin Zhang


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Abstract

Cationic polycarbonates are a class of very important polymers owing to their positively charged moieties and biodegradability. The positively charged moieties in cationic polycarbonates are able to combine anionic compounds such as nucleic acids and proteins to form the polyplexes. The biodegradability of cationic polycarbonates can reduce their toxicity. Here we summarized the reports on cationic polycarbonates via ring-opening polymerization from design and synthesis to applications. The synthetic methods of cationic polycarbonates mainly include ring-opening polymerization of cyclic carbonates containing amino groups and amination of functional polycarbonates. Cationic polycarbonates have been widely applied in biomedical fields such as drug release, gene delivery, and antimicrobial polymers.

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Source Journal

Polymer Chemistry

Polymer Chemistry
CiteScore: 8.6
Self-citation Rate: 7.3%
Articles per Year: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

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