![2,5-Furandione, dihydro-3-[3-(triethoxysilyl)propyl]- structure](https://static.chemtradehub.com/structs/936/93642-68-3-3b4b.webp "2,5-Furandione, dihydro-3-[3-(triethoxysilyl)propyl]- structure")
2,5-Furandione, dihydro-3-[3-(triethoxysilyl)propyl]-
CAS Number:
93642-68-3
Molecular Formula:
C13H24O6Si
One-step isothermal detection of multiple KRAS mutations by forming SNP specific hairpins on a gold nanoshell
Literature Information
Publication Date
2018-04-11
DOI
10.1039/C8AN00525G
Impact Factor
4.616
Authors
Chan Ho Chung, Joong Hyun Kim
View Original
Abstract
We developed a one-step isothermal method for typing multiple KRAS mutations using a designed set of primers to form a hairpin on a gold nanoshell upon being ligated by a SNP specific DNA ligase after binding of targets. As a result, we could detect as low as 20 attomoles of KRAS mutations within 1 h.
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Source Journal
Analyst
CiteScore:
7.8
Self-citation Rate:
5.6%
Articles per Year:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
Recommended Compounds
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(2S)-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)acetic acid
CAS Number:
102410-65-1
Molecular Formula:
C23H19NO4
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