Direct synthesis of indenes via a rhodium-catalyzed multicomponent Csp2–H annulation reaction
Literature Information
Pierre Querard, Chao-Jun Li
A highly efficient, direct and multicomponent route for the synthesis of indenes is reported herein. This process is catalyzed by a rhodium(III) complex and conducted under very mild conditions, making the overall process atom and step-economical. DFT mechanistic studies were performed to explore the mechanism of this reaction system.
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Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.












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