First synthesis of 2′,3′-epimino-carbocyclic nucleosides
Literature Information
Minoru Ishikura, Atsushi Murakami, Nobuya Katagiri
The preparation of 2′,3′-epimino-carbocyclic analogues of adenosine is reported. The reaction of p-tosyl azide with N-substituted 2-azabicyclo[2.2.1]hept-5-en-3-one (ABH) (1a) provided aziridine-fused ABH (2), which was converted to 2′,3′-epimino-carbocyclic nucleosides (11).
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Organic & Biomolecular Chemistry

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