Engineering molecularly imprinted polymers (MIPs) for the selective extraction and quantification of the novel psychoactive substance (NPS) methoxphenidine and its regioisomers
Literature Information
Publication Date
2018-04-12
DOI
10.1039/C8AN00131F
Impact Factor
4.616
Authors
J. W. Lowdon, S. M. O. Alkirkit, R. E. Mewis, D. Fulton, C. E. Banks, M. Peeters
View Original
Abstract
In this communication, we present the first developed Molecularly Imprinted Polymers (MIPs) for the specific detection of a New Psychoactive Substance (NPS); namely, methoxphenidine (MXP) and its regioisomers. Selectivity of the MIP towards MXP is studied by analysing mixtures and an acquired street sample with High Performance Liquid Chromatography coupled to UV detection. The study demonstrates that the engineered polymers selectively extract MXP from heterogeneous samples, which makes for a very powerful diagnostic tool that can detect traces of MXP in complicated NPS samples.
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Analyst
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Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
Recommended Compounds
![1-oxaspiro[4.4]nonan-6-one structure](https://static.chemtradehub.com/structs/134/134179-01-4-e051.webp "1-oxaspiro[4.4]nonan-6-one structure")
2-Methyl-2-propanyl 2-carbamimidoyl-1-piperidinecarboxylate
CAS Number:
1258640-98-0
Molecular Formula:
C11H21N3O2
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