Efficient intracellular delivery and improved biocompatibility of colloidal silver nanoparticles towards intracellular SERS immuno-sensing

Literature Information

Publication Date 2015-04-29
DOI 10.1039/C5AN00435G
Impact Factor 4.616
Authors

Vinay Bhardwaj, Supriya Srinivasan, Anthony J. McGoron


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Abstract

High throughput intracellular delivery strategies, electroporation, passive and TATHA2 facilitated diffusion of colloidal silver nanoparticles (AgNPs) are investigated for cellular toxicity and uptake using state-of-art analytical techniques. The TATHA2 facilitated approach efficiently delivered high payload with no toxicity, pre-requisites for intracellular applications of plasmonic metal nanoparticles (PMNPs) in sensing and therapeutics.

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