How is (6-Fluoro-3-pyridinyl)boronic acid (CAS: 351019-18-6) typically synthesized?

(6-Fluoro-3-pyridinyl)boronic acid can be synthesized through the reaction of 6-fluoro-3-pyridine carboxylic acid with a boron reagent such as pinacol boronate in the presence of a base like sodium carbonate. This synthesis yields a high purity product with good yield, typically around 85-90%. The process is selective and can be carried out under mild conditions, making it suitable for laboratory-scale production.