Bio-sensing with butterfly wings: naturally occurring nano-structures for SERS-based malaria parasite detection

Literature Information

Publication Date 2014-12-03
DOI 10.1039/C4CP04930F
Impact Factor 3.676
Authors

Matthew W. A. Dixon, Leann Tilley, Keith R. Bambery, Bayden R. Wood


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Abstract

Surface enhanced Raman scattering (SERS) is a powerful tool with great potential to provide improved bio-sensing capabilities. The current ‘gold-standard’ method for diagnosis of malaria involves visual inspection of blood smears using light microscopy, which is time consuming and can prevent early diagnosis of the disease. We present a novel surface-enhanced Raman spectroscopy substrate based on gold-coated butterfly wings, which enabled detection of malarial hemozoin pigment within lysed blood samples containing 0.005% and 0.0005% infected red blood cells.

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Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
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