Tuning the lower critical solution temperature of thermoresponsive polymers by biospecific recognition

Literature Information

Publication Date 2011-02-15
DOI 10.1039/C1PY00001B
Impact Factor 5.582
Authors

Jens Buller, André Laschewsky, Jean-François Lutz, Erik Wischerhoff


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Abstract

A thermosensitive statistical copolymer based on oligo(ethylene glycol) methacrylates incorporating biotin was synthesized by free radical copolymerisation. The influence of added avidin on its thermoresponsive behaviour was investigated. The specific binding of avidin to the biotinylated copolymers provoked a marked increase of the lower critical solution temperature.

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Polymer Chemistry

Polymer Chemistry
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