Tuning the lower critical solution temperature of thermoresponsive polymers by biospecific recognition
Literature Information
Jens Buller, André Laschewsky, Jean-François Lutz, Erik Wischerhoff
A thermosensitive statistical copolymer based on oligo(ethylene glycol) methacrylates incorporating biotin was synthesized by free radical copolymerisation. The influence of added avidin on its thermoresponsive behaviour was investigated. The specific binding of avidin to the biotinylated copolymers provoked a marked increase of the lower critical solution temperature.
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Polymer Chemistry

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