1,2-Fluorosulfenylation of unactivated alkenes with thiols and a fluoride source promoted by bromodimethylsulfonium bromide

Literature Information

Publication Date 2023-11-06
DOI 10.1039/D3CC05045A
Impact Factor 6.222
Authors

Zihui Yang, Jia Liu, Lan-Gui Xie


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Abstract

A practical method that enables the fluorosulfenylation of unactivated alkenes processed directly with thiols and fluoride salts is presented. Good to excellent efficiencies and functional group tolerance are observed for both alkene substrates and thiols. The procedure also allows the use of gaseous ethylene as a two-carbon building block for β-fluoro thioether products.

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