Expedient C–H allylation of sulfoxonium ylides: merging C–H and C–C/C–het bond activation

Literature Information

Publication Date 2023-10-31
DOI 10.1039/D3CC04507B
Impact Factor 6.222
Authors

Sharajit Saha, Hemanga Bhattacharyya, Pallab Karjee, Bijoy Debnath, Kshitiz Verma, Tharmalingam Punniyamurthy


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Abstract

Sulfoxonium ylide chelation-assisted C–H allylation of arenes has been accomplished utilizing strained vinyl carbo/heterocycles as the allyl surrogates via sequential C–H and C–C/het bond activation. Broad substrate scope, Co-catalysis, selectivity, and late-stage drug mutation are the important practical features.

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Chemical Communications

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