![4-[(2,4-Dihydroxyphenyl)diazenyl]-5-hydroxy-2,7-naphthalenedisulfonic acid structure](https://static.chemtradehub.com/structs/362/3627-01-8-79ac.webp "4-[(2,4-Dihydroxyphenyl)diazenyl]-5-hydroxy-2,7-naphthalenedisulfonic acid structure")
4-[(2,4-Dihydroxyphenyl)diazenyl]-5-hydroxy-2,7-naphthalenedisulfonic acid
CAS Number:
3627-01-8
Molecular Formula:
C16H12N2O9S2
Oligoagarose-g-polycaprolactone loaded nanoparticles for drug delivery applications
Literature Information
Publication Date
2010-10-29
DOI
10.1039/C0PY00311E
Impact Factor
5.582
Authors
Archana Bhaw-Luximon, Laila Musharat Meeram, Yeshma Jugdawa, William Helbert, Dhanjay Jhurry
View Original
Abstract
Well-defined oligoagarose-g-polycaprolactone copolymers of varying PCL chain lengths have been synthesised using protection/deprotection chemistry. The graft copolymers showed amphiphilic behaviour with spherical micelles in the size range 10 to 20 nm. Ketoprofen was loaded into the core of the micelles. The drug loading efficiency was shown to increase with the length of the hydrophobic PCL chain: 2% for PCL10 and 5.5% for PCL15. Sustained drug release was observed over a period of 72 h and was faster with shorter PCL chains.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
Recommended Compounds
![2-Methyl-2-propanyl [(2S)-1-hydroxy-3-(4-hydroxyphenyl)-2-propanyl]carbamate structure](https://static.chemtradehub.com/structs/833/83345-46-4-eec2.webp "2-Methyl-2-propanyl [(2S)-1-hydroxy-3-(4-hydroxyphenyl)-2-propanyl]carbamate structure")
2-Methyl-2-propanyl [(2S)-1-hydroxy-3-(4-hydroxyphenyl)-2-propanyl]carbamate
CAS Number:
83345-46-4
Molecular Formula:
C14H21NO4
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