Formation and dissolution of hen egg white lysozyme amyloid fibrils in protic ionic liquids

Literature Information

Publication Date 2009-02-02
DOI 10.1039/B817590J
Impact Factor 6.222
Authors

Nolene Byrne, C. Austen Angell


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Abstract

The formation of amyloid fibrils from non-disease-related proteins demonstrates that any protein can adopt this “rogue” form; we show that it is possible to use protic ionic liquids to fibrilize hen egg white lysozyme, and then subsequently to dissolve the fibrils with up to 72% restoration of enzymatic activity.

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