Recognition of lectin with a high signal to noise ratio: carbohydrate-tri(ethylene glycol)-alkanethiol co-adsorbed monolayer
Literature Information
Yukari Sato, Kyoko Yoshioka, Mutsuo Tanaka, Teiichi Murakami, Miho Neide Ishida, Osamu Niwa
Densely packed co-adsorbed ultrathin mono molecular layers of short tri(ethylene glycol)-alkanethiolate (for repelling proteins) and maltoside terminated alkanethiolate (for capturing lectin) provided an extremely high signal to noise ratio surface: the repelling molecules, which had two different functions (highly flexible-hydrophilic arm and rigid packing tail group), worked as “nano barriers” in the recognition monolayer.
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