5-Chloro-2-hydroxybenzoic acid

Basic Information

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CAS Number

321-14-2

Molecular Formula

C7H5ClO3

Molecular Weight

172.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

172.0 to 178.0 deg-C

Boiling Point

244.67°C (rough estimate)

Water Solubility

1 g/L (20 ºC)

Flash Point

147.6°C

Solubility

1g/l

Refractive Index

1.4580 (estimate)

SMILES

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OC(=O)c1cc(Cl)ccc1O

InChI

InChI=1S/C7H5ClO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,(H,10,11)

InChIKey

NKBASRXWGAGQDP-UHFFFAOYSA-N

LogP

1.7437999999999998

Topological Polar Surface Area

57.53 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

160

Safety Information

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GHS Hazard Pictograms

H301

H315

H319

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

5-Chloro-2-hydroxybenzoic acid
2-Hydroxy-5-Chloro Benzoic Acid
5-Chlorosalicylic acid
5 CSA
5-chloro-2-hydroxy-benzoic acid
5-Chlorosalicyclic acid
5-chloro-salicylic acid
Benzoic acid,5-chloro-2-hydroxy
Salicylic acid,5-chloro
tert-butyl carbazate
CSA
5-Chloro-2-hydroxybenzoic Acid

MDL Number

MFCD00002457

Customs Code

29182990

FAQ

What is 5-Chloro-2-hydroxybenzoic acid (CAS: 321-14-2)?

5-Chloro-2-hydroxybenzoic acid, also known as 5-chlorosalicylic acid, is an aromatic carboxylic acid with the chemical formula C7H6ClO3. It is a white crystalline solid that is soluble in water and organic solvents. This compound is characterized by its chlorine substituent on the benzene ring and hydroxyl group at the 2-position, making it a valuable intermediate in organic synthesis.

What are the main uses of 5-Chloro-2-hydroxybenzoic acid (CAS: 321-14-2)?

5-Chloro-2-hydroxybenzoic acid is widely used in pharmaceuticals as a precursor for the synthesis of various drugs, including anti-inflammatory and antipyretic agents. It also finds applications in the production of dyes, pesticides, and other industrial chemicals. In research, it serves as a key compound for developing new materials and studying chemical reactivity.

Is 5-Chloro-2-hydroxybenzoic acid (CAS: 321-14-2) safe?

5-Chloro-2-hydroxybenzoic acid is generally considered safe when handled properly. However, it may cause skin and eye irritation, so protective measures such as gloves and safety goggles are recommended. It is important to follow safety guidelines and proper ventilation to minimize exposure risks in laboratory or industrial settings.

How should 5-Chloro-2-hydroxybenzoic acid (CAS: 321-14-2) be stored?

5-Chloro-2-hydroxybenzoic acid should be stored in a cool, dry, and well-ventilated area, away from light. It is best kept in a sealed container to prevent moisture absorption. Storage at temperatures below 25°C is recommended to maintain stability and avoid degradation of the compound.