Controlling the formation of 1 out of 64 stereoisomers using organocatalysis

Literature Information

Publication Date 2008-06-09
DOI 10.1039/B806418K
Impact Factor 6.222
Authors

Søren Bertelsen, Rasmus L. Johansen, Karl Anker Jørgensen


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Abstract

The formation of 1 out of 64 stereoisomers, i.e. controlling the creation of 6 stereocenters, of important optically active bicyclo[3.3.1]non-2-ene compounds, has been achieved using organocatalysis; the reaction proceeds with excellent stereocontrol and can be carried out with the generation of enantiopure products using chromatography-free procedures.

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Cover

DOI: 10.1039/C7CP90128C

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