Asymmetric multifunctional organocatalytic Michael addition of nitroalkanes to α,β-unsaturated ketones

Literature Information

Publication Date 2008-05-16
DOI 10.1039/B804540B
Impact Factor 6.222
Authors

Pengfei Li, Yongcan Wang, Jinxing Ye


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Abstract

Cinchona alkaloid derived primary amine thioureas organocatalyzed Michael addition of nitroalkanes to enones in good yield and up to 98% ee and offered a new way to construct quaternary stereocenters from enones and nitroalkanes.

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