Rhodium-catalyzed enantioselective desymmetrization of bicyclic hydrazines with alkynylboronic esters
Literature Information
Stefano Crotti, Ferruccio Bertolini, Franco Macchia, Mauro Pineschi
The first successful asymmetric transfer of rhodium–alkynyl species to symmetrical strained alkenes has been realized starting from bicyclic hydrazines and alkynylboronic esters.
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![4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl acetate structure 4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl acetate structure](https://static.chemtradehub.com/structs/740/740081-22-5-f58f.webp)