A chemo- and regio-selective three-component dihydropyrimidinone synthesis
Literature Information
Chris D. Bailey, Chris E. Houlden, Grégory L. J. Bar, Guy C. Lloyd-Jones, Kevin I. Booker-Milburn
A selective three-component coupling, involving co-condensation of aldehyde pairs with substituted ureas under Lewis acid catalysis, provides rapid access to highly functionalised dihydropyrimidinones; sulfamides react analogously.
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