Palladium-catalysed regioselective addition reaction of ethyl phenylphosphinate with terminal acetylenes: ligand- and solvent-dependent regioselectivity‡

Literature Information

Publication Date 2007-04-27
DOI 10.1039/B703165C
Impact Factor 6.222
Authors

Satish Kumar Nune, Masato Tanaka


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Abstract

Palladium–1,2-bis(diphenylphosphino)ethane complex catalyses regioselective Markovnikov addition of ethyl phenylphosphinate to terminal alkynes in toluene, while the use of tri-tert-butylphosphine as the ligand or ethanol as the solvent leads to regioselectivity reversal.

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