Alkylation of active methylene compounds with alcohols catalyzed by an iridium complex

Literature Information

Publication Date 2007-04-30
DOI 10.1039/B702293J
Impact Factor 6.222
Authors

Masao Morita, Yasushi Obora, Yasutaka Ishii


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Abstract

Base-free catalytic α-alkylation of active methylene compounds with primary alcohols was successfully achieved using an [IrCl(cod)]2 complex in the presence of PPh3 to afford the corresponding saturated α-alkylated products in good yields.

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