Alkylation of active methylene compounds with alcohols catalyzed by an iridium complex
Literature Information
Masao Morita, Yasushi Obora, Yasutaka Ishii
Base-free catalytic α-alkylation of active methylene compounds with primary alcohols was successfully achieved using an [IrCl(cod)]2 complex in the presence of PPh3 to afford the corresponding saturated α-alkylated products in good yields.
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