Simulation of maintenance of the epidermis

Literature Information

Publication Date 2002-09-04
DOI 10.1039/B205795F
Impact Factor 3.676
Authors

Bengt Kasemo


View Original

Abstract

We propose a 3D lattice Monte Carlo model of self-renewal of the epidermis, including division of cells located in the innermost layer, death of cells in the upper layers, and cell diffusion between the layers. The results of simulations indicate that the dependence of the epidermis thickness, l, on the model parameters is extremely weak. For example, the two orders of magnitude increase in the cell life expectancy results in increase of l only by a factor of two.

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Source Journal

Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
CiteScore: 5.5
Self-citation Rate: 10.3%
Articles per Year: 3036

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.

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