Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amideoligonucleotide mimics (POM)

Literature Information

Publication Date 2004-01-28
DOI 10.1039/B315768G
Impact Factor 6.222
Authors

T. H. Samuel Tan, David T. Hickman, Jordi Morral, Ian G. Beadham, Jason Micklefield


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Abstract

Adeninyl POM was prepared using solid-phase peptide chemistry and shown to exhibit higher affinity for complementary DNA and RNA than the corresponding adeninyl PNA.

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