Compound Q&A
How is (2S,3S)-2-Hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-(2-naphthyl)propanoic acid (CAS: 959583-98-3) typically synthesized?
Answer
![(2S,3S)-2-Hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-(2-naphthyl)propanoic acid](https://static.chemtradehub.com/structs/959/959583-98-3-483c.webp "(2S,3S)-2-Hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-(2-naphthyl)propanoic acid")
(2S,3S)-2-Hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-(2-naphthyl)propanoic acid can be synthesized via the coupling of 2-naphthylamine and a protected carboxylic acid derivative. The synthesis involves the use of a protecting group to prevent hydrolysis of the naphthylamine. Commonly used catalysts include HOBt and DCC, and the yield can be up to 75%. The reaction is typically carried out in anhydrous organic solvents at room temperature.
About
CAS No
959583-98-3
English Name
(2S,3S)-2-Hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-(2-naphthyl)propanoic acid
Molecular Formula
C18H21NO5
Molecular Weight
331.36800000000005 g/mol
SMILES
CC(C)(C)OC(=O)NC(C1=CC2=CC=CC=C2C=C1)C(C(=O)O)O
InChIKey
DQUFRNIKBQMWFX-GJZGRUSLSA-N
Last Updated: 2026-03-23 12:56
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