2-hydroxypropyl prop-2-enoate

Basic Information

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CAS Number

999-61-1

Molecular Formula

C6H10O3

Molecular Weight

130.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

225 ºC

Density

1.06 g/cm3

Flash Point

79.9±15.4 ºC,

Refractive Index

1.4315 (estimate)

SMILES

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CC(O)COC(=O)C=C

InChI

InChI=1S/C6H10O3/c1-3-6(8)9-4-5(2)7/h3,5,7H,1,4H2,2H3

InChIKey

GWZMWHWAWHPNHN-UHFFFAOYSA-N

LogP

0.09640000000000004

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

109

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 8 Class 8

Class 6.1 Class 6.1

Synonyms & References

English

2-Hydroxypropyl acrylate
2-HYDROXYPROPYL ACRYLATE HPA
2-Propenoic acid,2-hydroxypropyl ester
1,2-propanediol 1-acrylate
acrylic acid 2-hydroxypropyl ester
beta-hydroxypropyl acrylate
2HPA
Bisomer HPA
HOP-A
HPA
Kayarad HPA
Light Ester HOP-A
2-propenoic acid 2-hydroxypropyl ester
2-hydroxypropylacrylate

MDL Number

MFCD00021900

FAQ

What are the physical and chemical properties of 2-hydroxypropyl prop-2-enoate (CAS: 999-61-1)?

2-Hydroxypropyl prop-2-enoate (CAS: 999-61-1) is a clear, colorless liquid with a molecular weight of approximately 134.14 g/mol. It has a pKa of about 4.5 and a boiling point of around 147°C. The compound is slightly soluble in water but miscible with most organic solvents. It exhibits moderate reactivity with nucleophiles and can undergo esterification reactions.

How is 2-hydroxypropyl prop-2-enoate (CAS: 999-61-1) typically synthesized?

2-Hydroxypropyl prop-2-enoate (CAS: 999-61-1) can be synthesized by the reaction of prop-2-enoic acid with 2-hydroxypropyl alcohol. This process often involves the use of a strong acid catalyst such as sulfuric acid. The reaction is exothermic, and high yields are typically achieved under controlled conditions with good selectivity.

What industries use 2-hydroxypropyl prop-2-enoate (CAS: 999-61-1)?

2-Hydroxypropyl prop-2-enoate (CAS: 999-61-1) is used in various industries. It is particularly valuable in the pharmaceutical industry for the synthesis of certain drugs. In the polymer industry, it serves as a monomer for the production of specialty polymers. It also finds applications in the manufacturing of sensors, semiconductors, and as a monomer in advanced coatings and adhesives.

What precautions should be taken when handling 2-hydroxypropyl prop-2-enoate (CAS: 999-61-1)?

When handling 2-hydroxypropyl prop-2-enoate (CAS: 999-61-1), it is crucial to use appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up immediately using absorbent materials, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.