1-Methyl-3-pyrrolidinol

Basic Information

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CAS Number

99445-21-3

Molecular Formula

C5H11NO

Molecular Weight

101.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CN1CCC(C1)O

InChI

InChI=1S/C5H11NO/c1-6-3-2-5(7)4-6/h5,7H,2-4H2,1H3

InChIKey

FLVFPAIGVBQGET-UHFFFAOYSA-N

LogP

-0.3172000000000001

Topological Polar Surface Area

23.47 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

65.1

Synonyms & References

English

UNII-CGW2AL7PQ7
Q-201484
EN300-204124
1-methyl-pyrrolidin-3ol
13220-33-2
FT-0605035
SB10211
AM20080233
SCHEMBL129605
MFCD00003176
NSC-89279
1-Methylpyrrolidin-3-ol
PB17320
NS00051700
EINECS 236-189-3
PENTAERYTHRITOLTETRA(MERCAPTOACETATE)
DTXSID10864377
M2115
N-METHYL-3-HYDROXYPYRROLIDINE
NSC 89279
3-hydroxy-n-methylpyrrolidine
1-methyl-pyrrolidin-3-ol
1-METHYL-3-HYDROXYPYRROLIDINE
1-Methyl-3-pyrrolidinol, 95%
3-Pyrrolidinol, 1-methyl-
SY003953
AKOS009157110
MFCD03788748
l-methyl-3-pyrrolidinol
99445-21-3
CGW2AL7PQ7

MDL Number

MFCD00003176

FAQ

What are the physical and chemical properties of 1-Methyl-3-pyrrolidinol (CAS: 99445-21-3)?

1-Methyl-3-pyrrolidinol (CAS: 99445-21-3) is a colorless to slightly yellow liquid with a molecular weight of 105.14 g/mol. It has a pungent odor and is slightly soluble in water but miscible with ethanol and other organic solvents. It is readily reactive in the presence of strong acids and bases. A crystalline form exists, but it is less common and less stable than the liquid form.

How is 1-Methyl-3-pyrrolidinol (CAS: 99445-21-3) typically synthesized?

1-Methyl-3-pyrrolidinol is typically synthesized via the reduction of 1-methyl-3-pyrrolone using sodium borohydride or lithium aluminum hydride as the reducing agent. This process yields high selectivity and good yields. The reaction is usually carried out in anhydrous organic solvents at low temperatures to prevent side reactions.

What industries use 1-Methyl-3-pyrrolidinol (CAS: 99445-21-3)?

1-Methyl-3-pyrrolidinol (CAS: 99445-21-3) is used in various industries, including pharmaceuticals for drug synthesis, polymer production as a chain extender, and in the production of sensors and semiconductors due to its unique reactivity and solubility properties.

What precautions should be taken when handling 1-Methyl-3-pyrrolidinol (CAS: 99445-21-3)?

When handling 1-Methyl-3-pyrrolidinol (CAS: 99445-21-3), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or fume hood. Spills should be cleaned up immediately with appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for specific safety instructions.