1-Methyl-3-pyrrolidinol(CAS: 99445-21-3)

1-Methyl-3-pyrrolidinol (CAS: 99445-21-3) is a colorless to slightly yellow liquid with a molecular weight of 105.14 g/mol. It has a pungent odor and is slightly soluble in water but miscible with ethanol and other organic solvents. It is readily reactive in the presence of strong acids and bases. A crystalline form exists, but it is less common and less stable than the liquid form.

1-Methyl-3-pyrrolidinol is typically synthesized via the reduction of 1-methyl-3-pyrrolone using sodium borohydride or lithium aluminum hydride as the reducing agent. This process yields high selectivity and good yields. The reaction is usually carried out in anhydrous organic solvents at low temperatures to prevent side reactions.

1-Methyl-3-pyrrolidinol (CAS: 99445-21-3) is used in various industries, including pharmaceuticals for drug synthesis, polymer production as a chain extender, and in the production of sensors and semiconductors due to its unique reactivity and solubility properties.

When handling 1-Methyl-3-pyrrolidinol (CAS: 99445-21-3), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or fume hood. Spills should be cleaned up immediately with appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for specific safety instructions.