Lymecycline (85%)

Basic Information

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CAS Number

992-21-2

Molecular Formula

C29H38N4O10

Molecular Weight

602.64 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

192.5°C

Boiling Point

648.97°C (rough estimate)

Density

1.53

Refractive Index

1.5500 (estimate)

SMILES

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CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)NCNCCCCC(C(=O)O)N)N(C)C)O

InChI

InChI=1S/C29H38N4O10/c1-28(42)13-7-6-9-17(34)18(13)22(35)19-14(28)11-15-21(33(2)3)23(36)20(25(38)29(15,43)24(19)37)26(39)32-12-31-10-5-4-8-16(30)27(40)41/h6-7,9,14-16,21,31,34,36-37,42-43H,4-5,8,10-12,30H2,1-3H3,(H,32,39)(H,40,41)/t14-,15-,16-,21-,28+,29-/m0/s1

InChIKey

AHEVKYYGXVEWNO-UEPZRUIBSA-N

LogP

-0.45419999999999566

Topological Polar Surface Area

242.97999999999996 Å²

Hydrogen Bond Donor/Acceptor

10 / 14

Complexity

1230

Synonyms & References

English

Lymecycline [INN:BAN]
CS-0025613
Tetralisal
L-Lysine, N6-(((((4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenyl)carbonyl)amino)methyl)-
DB00256
Armyl
LYMECYCLINE [MI]
Tetracyclinemethylenelysine
CHEMBL2103929
Limeciclina [INN-Spanish]
AKOS016340328
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, lysinemethylene deriv.
N2-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline
tetracycline-L Methylene-Lysine
Ciclisin
Ciclolysine
Q897051
LYMECYCLINE [EP MONOGRAPH]
HY-106339
L-Lysine,N6-[[[[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenyl]carbonyl]amino]methyl]-
(2S)-6-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2-yl]formamido}methyl)amino]-2-aminohexanoic acid
D06884
N(sup 2)-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline
Tetracycline-L-methylenelysine
7D6EM3S13P
SCHEMBL23248015
N(6)-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2-yl]carbonyl}amino)methyl]-L-lysine
Tetraciclina-L-metilenlisina
Lymecycline (85%)
(2S)-6-[[[(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carbonyl]amino]methylamino]-2-aminohexanoic acid
Lymecyclinum [INN-Latin]

MDL Number

MFCD01716199

FAQ

What are the physical and chemical properties of Lymecycline (CAS: 992-21-2)?

Lymecycline (CAS: 992-21-2) is a semi-synthetic tetracycline antibiotic with a crystalline form. Its molecular weight is approximately 454.51 g/mol. Lymecycline has low solubility in water but is soluble in dilute acids. It is stable under normal conditions but can react with strong oxidizing agents. It is used in pharmaceuticals and veterinary medicine due to its broad-spectrum activity.

How is Lymecycline (CAS: 992-21-2) typically synthesized?

Lymecycline (CAS: 992-21-2) is typically synthesized through a series of steps, starting from chlortetracycline, followed by hydrogenation, reduction, and cyclization. Common catalysts include palladium on carbon. The synthesis yields a high purity product with good selectivity and yield, making it suitable for pharmaceutical applications.

What industries use Lymecycline (CAS: 992-21-2)?

Lymecycline (CAS: 992-21-2) is primarily used in the pharmaceutical industry for treating bacterial infections in humans and animals. It is also utilized in veterinary medicine to prevent and treat various bacterial diseases in livestock and poultry. Additionally, it has applications in agriculture, although its use is limited due to antibiotic resistance concerns.

What precautions should be taken when handling Lymecycline (CAS: 992-21-2)?

When handling Lymecycline (CAS: 992-21-2), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Store it in a cool, dry place away from direct sunlight. Use a fume hood during handling to avoid inhalation. In case of a spill, immediately clean it up using appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for proper disposal.