N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide

Basic Information

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CAS Number

98967-40-9

Molecular Formula

C12H9F2N5O2S

Molecular Weight

325.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

250-251°

Density

1.6600

Refractive Index

1.703

SMILES

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Cc1ccn2c(n1)nc(n2)S(=O)(=O)Nc1c(F)cccc1F

InChI

InChI=1S/C12H9F2N5O2S/c1-7-5-6-19-11(15-7)16-12(17-19)22(20,21)18-10-8(13)3-2-4-9(10)14/h2-6,18H,1H3

InChIKey

RXCPQSJAVKGONC-UHFFFAOYSA-N

LogP

1.51172

pKa

4.6(at 25℃)

Topological Polar Surface Area

89.25 Å²

Hydrogen Bond Donor/Acceptor

1 / 7

Complexity

492

Safety Information

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Hazard Statement

H332 Harmful if inhaled
Acute toxicity, inhalation

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Toxicity

LD50 in rats (mg/kg): >5000 orally; in rabbits (mg/kg): >2000 dermally (Kleschick, 1992)

Synonyms & References

English

N-(2,6-Difluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide
2-(2,6-DIFLUOROPHENYLSULPHAMOYL)-5-METHYL-[1,2,4]-TRIAZOLO[1,5-A]PYRIDINE
BROADSTRIKE(R)
FLUMETSULAM
N-(2,6-DIFLUOROPHENYL)-5-METHYL-[1,2,4]TRIAZOLO[1,5-A]-PYRIMIDINE-2-SULFONAMIDE
PRESIDE(R)
SCORPION(R)
(1,2,4)triazolo(1,5-a)pyrimidine-2-sulfonamide,n-(2,6-difluorophenyl)-5-methyl
de498
n-(2,6-difluorophenyl)-5-methyl-(1,2,4)triazolo(1,5-a)pyrimidine-2-sulfonami
xrd498
2′,6′-difluoro-5-methyl(1,2,4)triazolo(1,5-a)pyrimidine-2-sulfonanilide
Flumetaulam
flumetsulam (bsi, pa e-iso, ansi)
N-(2,6-Difluorophenyl)-5-methyl-1,2,4-triazol[1,5-a]pyrimidine-2-sulfonamide
N-(2,6-Difluorophenyl)-7-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulphonamide
Aurora
Flumetsulam Solution
2',6'-difluoro-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonanilide
2',6'-Difluoro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonanilide
Broadstrike
N-(2,6-difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide
2′,6′-Difluoro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonanilide

MDL Number

MFCD04089841

FAQ

What are the physical and chemical properties of N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide (CAS: 98967-40-9)?

N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide is a crystalline solid with a molecular weight of approximately 314.21 g/mol. It has low water solubility and moderate solubility in organic solvents. It is a stable compound under normal conditions but may react with strong acids or bases. It is not flammable and has a melting point of around 220-225°C.

How is N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide (CAS: 98967-40-9) typically synthesized?

N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide is synthesized using a multi-step process involving the preparation of the 2,6-difluorophenyl group followed by coupling with 5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide. The reaction is typically catalyzed by a transition metal and proceeds with a good yield. The product undergoes rigorous purification steps to achieve the desired purity.

What industries use N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide (CAS: 98967-40-9)?

N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide is primarily used in the pharmaceutical industry for its potential as an antiviral agent. It also finds applications in the development of sensors and as a component in certain polymer systems. The compound's unique chemical structure makes it valuable in the research and development of new materials and drugs.

What precautions should be taken when handling N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide (CAS: 98967-40-9)?

When handling N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate procedures, and the material safety data sheet (MSDS) should be consulted for detailed safety information. The compound is not particularly hazardous, but proper handling practices are still necessary to ensure safety.