N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide(CAS: 98967-40-9)

N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide is a crystalline solid with a molecular weight of approximately 314.21 g/mol. It has low water solubility and moderate solubility in organic solvents. It is a stable compound under normal conditions but may react with strong acids or bases. It is not flammable and has a melting point of around 220-225°C.

N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide is synthesized using a multi-step process involving the preparation of the 2,6-difluorophenyl group followed by coupling with 5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide. The reaction is typically catalyzed by a transition metal and proceeds with a good yield. The product undergoes rigorous purification steps to achieve the desired purity.

N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide is primarily used in the pharmaceutical industry for its potential as an antiviral agent. It also finds applications in the development of sensors and as a component in certain polymer systems. The compound's unique chemical structure makes it valuable in the research and development of new materials and drugs.

When handling N-(2,6-Difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate procedures, and the material safety data sheet (MSDS) should be consulted for detailed safety information. The compound is not particularly hazardous, but proper handling practices are still necessary to ensure safety.