4-Bromo-2-phenylpyridine

Basic Information

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CAS Number

98420-98-5

Molecular Formula

C11H8BrN

Molecular Weight

234.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Density

1.426±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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C1=CC=C(C=C1)C2=NC=CC(=C2)Br

InChI

InChI=1S/C11H8BrN/c12-10-6-7-13-11(8-10)9-4-2-1-3-5-9/h1-8H

InChIKey

HCQHVQSQHXZRGA-UHFFFAOYSA-N

LogP

3.5111000000000017

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

154

Synonyms & References

English

4-bromo -2-phenylpyridine
Fudosteine/(R)-2-Amino-3-(3-hydroxypropylthio)propionic acid
4-bromo-2-phenyl-pyridine
MFCD11656282
Pyridine,4-bromo-2-phenyl-
HCQHVQSQHXZRGA-UHFFFAOYSA-N
2-phenyl-4-bromopyridine
4-BROMO-2-PHENYLPYRIDINE
FD10576
A850484
98420-98-5
Pyridine, 4-bromo-2-phenyl-
CS-0149623
FT-0748452
AKOS015945624
DTXSID40542252
SCHEMBL4803
J-514689
4-Bromo-2-phenylpyridine
4-Bromo-2-phenyl-pyridine
4-Bromo-2-phenylypridine
Pyridine,4-bromo-2-phenyl

MDL Number

MFCD11656282

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Bromo-2-phenylpyridine (CAS: 98420-98-5)?

4-Bromo-2-phenylpyridine is a crystalline solid with a molecular weight of approximately 247.02 g/mol. It has a low water solubility but is soluble in common organic solvents such as ethanol and dichloromethane. It is moderately reactive with nucleophiles and can undergo substitution reactions. The compound is stable under normal conditions but requires careful handling in the presence of strong reducing agents.

How is 4-Bromo-2-phenylpyridine (CAS: 98420-98-5) typically synthesized?

4-Bromo-2-phenylpyridine is typically synthesized via the bromination of 2-phenylpyridine. This process involves the reaction of 2-phenylpyridine with bromine in the presence of a base such as sodium hydroxide. The yield and selectivity of the reaction can be influenced by the choice of solvent and reaction conditions.

What industries use 4-Bromo-2-phenylpyridine (CAS: 98420-98-5)?

4-Bromo-2-phenylpyridine is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also applied in the polymer industry for the development of new materials with specific properties. Additionally, it has applications in the semiconductor industry as a precursor for electronic functional materials.

What precautions should be taken when handling 4-Bromo-2-phenylpyridine (CAS: 98420-98-5)?

When handling 4-Bromo-2-phenylpyridine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. It is recommended to consult the Material Safety Data Sheet (MSDS) for detailed safety information.