4-Bromo-2-phenylpyridine(CAS: 98420-98-5)

4-Bromo-2-phenylpyridine is a crystalline solid with a molecular weight of approximately 247.02 g/mol. It has a low water solubility but is soluble in common organic solvents such as ethanol and dichloromethane. It is moderately reactive with nucleophiles and can undergo substitution reactions. The compound is stable under normal conditions but requires careful handling in the presence of strong reducing agents.

4-Bromo-2-phenylpyridine is typically synthesized via the bromination of 2-phenylpyridine. This process involves the reaction of 2-phenylpyridine with bromine in the presence of a base such as sodium hydroxide. The yield and selectivity of the reaction can be influenced by the choice of solvent and reaction conditions.

4-Bromo-2-phenylpyridine is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also applied in the polymer industry for the development of new materials with specific properties. Additionally, it has applications in the semiconductor industry as a precursor for electronic functional materials.

When handling 4-Bromo-2-phenylpyridine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. It is recommended to consult the Material Safety Data Sheet (MSDS) for detailed safety information.