2-Fluoro-D-phenylalanine

Basic Information

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CAS Number

97731-02-7

Molecular Formula

C9H10FNO2

Molecular Weight

183.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

242-252°C

Specific Rotation

14 º (c=1% in H2O)

SMILES

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C1=CC=C(C(=C1)CC(C(=O)O)N)F

InChI

InChI=1S/C9H10FNO2/c10-7-4-2-1-3-6(7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m1/s1

InChIKey

NYCRCTMDYITATC-MRVPVSSYSA-N

LogP

0.7801000000000002

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

187

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(R)-2-Amino-3-(2-fluorophenyl)propanoic acid
o-Fluoro-D-phenylalanine
D-2-Fluorophe
3-(2-Fluoropheny)-D-alanine
2-Fluoro-D-phenylalanine
D-2-FLUOROPHENYLALANINE
D-2-F-Phe-OH
H-D-Phe(2-F)-OH
2-Fluoro-D-Phenylalanine (Sum of Enantiomers)
2-FLUORO-D-PHE
(2R)-2-amino-3-(2-fluorophenyl)propanoic acid
(R)-2-Fluorophenylalanine Hydrochloride Salt
H-D-Phe(2-F)-OH.HCl
PubChem23304
(r)-o-fluorophenylalanine
D-2-Fluoro phenylalanine
VZ24655
AM83328
RTR-0
2-Fluoro-D-phenylalanine (ACI)
D
(2R)-2-Amino-3-(2-fluorophenyl)propanoic acid
D-2-Fluorophenylalanine
PD196711
J-004866
D-2-FLUOROPHE
(R)-3-(2-fluorophenyl)-2-aminopropanoic acid
AC-5822
MFCD00066447
(2R)-2-azaniumyl-3-(2-fluorophenyl)propanoate
97731-02-7

MDL Number

MFCD00066447

FAQ

What are the physical and chemical properties of 2-Fluoro-D-phenylalanine (CAS: 97731-02-7)?

2-Fluoro-D-phenylalanine is a crystalline compound with a molecular weight of approximately 185.14 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. Chemically, it is less reactive than the parent compound D-phenylalanine, making it suitable for specific synthetic applications. It exhibits good stability under anhydrous conditions but should be handled with care in the presence of moisture.

How is 2-Fluoro-D-phenylalanine (CAS: 97731-02-7) typically synthesized?

2-Fluoro-D-phenylalanine is typically synthesized through the fluorination of D-phenylalanine using Lewis acids such as phosphorus pentachloride (PCl5) or fluorine gas (F2). The reaction is carried out under anhydrous conditions to prevent side reactions. The yield is generally high, and the product is usually obtained in a crystalline form, facilitating easy purification.

What industries use 2-Fluoro-D-phenylalanine (CAS: 97731-02-7)?

2-Fluoro-D-phenylalanine is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds. It also finds applications in the polymer industry for the development of novel materials with specific properties. Additionally, it is explored in the fields of sensors and semiconductors for its unique chemical and biological characteristics.

What precautions should be taken when handling 2-Fluoro-D-phenylalanine (CAS: 97731-02-7)?

When handling 2-Fluoro-D-phenylalanine, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.