Compound Q&A

How is 2-Fluoro-D-phenylalanine (CAS: 97731-02-7) typically synthesized?

Answer

2-Fluoro-D-phenylalanine
2-Fluoro-D-phenylalanine is typically synthesized through the fluorination of D-phenylalanine using Lewis acids such as phosphorus pentachloride (PCl5) or fluorine gas (F2). The reaction is carried out under anhydrous conditions to prevent side reactions. The yield is generally high, and the product is usually obtained in a crystalline form, facilitating easy purification.

About

CAS No 97731-02-7
English Name 2-Fluoro-D-phenylalanine
Molecular Formula C9H10FNO2
Molecular Weight 183.18 g/mol
SMILES C1=CC=C(C(=C1)CC(C(=O)O)N)F
InChIKey NYCRCTMDYITATC-MRVPVSSYSA-N
Last Updated: 2025-09-29 09:43

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