2-Amino-3,3,3-trifluoropropanoic acid hydrochloride

Basic Information

View in Editor

CAS Number

96105-72-5

Molecular Formula

C3H5ClF3NO2

Molecular Weight

179.52 g/mol

Basic Physical Properties

Melting Point

225-235 °C

SMILES

View in Editor

C(C(=O)O)(C(F)(F)F)N.Cl

InChI

InChI=1S/C3H4F3NO2.ClH/c4-3(5,6)1(7)2(8)9;/h1H,7H2,(H,8,9);1H

InChIKey

MRYBJJRPTNOPQK-UHFFFAOYSA-N

LogP

0.3824000000000002

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

121

Safety Information

View Safety Information

GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-Amino-3,3,3-trifluoropropanoic acid hydrochloride
2-Amino-3,3,3-trifluoro-propionic acid hydrochloride
2-AMINO-4,4,4-TRIFLUOROBUTYRIC ACID HYDROCHLORIDE
3,3,3-TRIFLUOROALANINE HYDROCHLORIDE
2-Amino-3,3,3-trifluoropropionic acid hydrochloride
3,3,3-Trifluoroalanin hydrochloride
3,3,3-Trifluoroalanine HCl
BESTIPHARMA 549-246
C3H4F3NO2 hydrochloride
trifluoroalanine hydrochloride
Alanine, 3,3,3-trifluoro-, hydrochloride (9CI)
3,3,3-Trifluoroalanine hydrochloride
3,3,3-Trifluoroalaninehydrochloride
2-amino-3,3,3-trifluoro-propanoic acid hydrochloride
2-amino-3,3,3-trifluoropropanoicacidhydrochloride
DB-001213
EN300-138873
MFCD04973034
Z1837073442
3,3,3-Trifluoro-DL-alanine hydrochloride, 95%
SCHEMBL19837180
2-amino-3,3,3-trifluoropropanoic acid;hydrochloride
2-AMINO-3,3,3-TRIFLUOROPROPANOIC ACID HCL
C3H5ClF3NO2
DTXSID70557415
W17058
MRYBJJRPTNOPQK-UHFFFAOYSA-N
96105-72-5
AKOS005063871
3,3,3-TRIFLUORO-DL-ALANINE HYDROCHLORIDE
CS-0059723

MDL Number

MFCD04973034

Customs Code

2922499990

FAQ

What are the physical and chemical properties of 2-Amino-3,3,3-trifluoropropanoic acid hydrochloride (CAS: 96105-72-5)?

2-Amino-3,3,3-trifluoropropanoic acid hydrochloride is a white crystalline solid with a molecular weight of approximately 268.63 g/mol. It has a high solubility in water and exhibits basic properties due to the presence of the amino group. This compound is less reactive than other carboxylic acids due to the electron-withdrawing trifluoro substituents. It is stable under normal conditions but should be stored away from strong oxidizing agents.

How is 2-Amino-3,3,3-trifluoropropanoic acid hydrochloride (CAS: 96105-72-5) typically synthesized?

2-Amino-3,3,3-trifluoropropanoic acid hydrochloride is often synthesized by the reaction of 3,3,3-trifluoropropylamine with carbon dioxide under basic conditions to form the carboxamide, followed by acidification to form the hydrochloride salt. Common solvents include dimethyl sulfoxide (DMSO) and water. The reaction typically has good yield and selectivity, with the trifluoro substituents leading to stable intermediates.

What industries use 2-Amino-3,3,3-trifluoropropanoic acid hydrochloride (CAS: 96105-72-5)?

2-Amino-3,3,3-trifluoropropanoic acid hydrochloride finds applications in the pharmaceutical industry as an intermediate for the synthesis of various medicinal compounds. It also has potential uses in the polymer industry for the development of functional polymers with specific properties. Additionally, the compound is of interest in sensor technology and semiconductor manufacturing due to its chemical stability and functional groups.

What precautions should be taken when handling 2-Amino-3,3,3-trifluoropropanoic acid hydrochloride (CAS: 96105-72-5)?

When handling 2-Amino-3,3,3-trifluoropropanoic acid hydrochloride, it is important to wear appropriate personal protective equipment (PPE) including safety goggles, gloves, and lab coat. Ensure the work is conducted in a well-ventilated area or a fume hood to avoid inhalation of the compound. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly rinsed. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.