Omeprazole Magnesium

Basic Information

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CAS Number

95382-33-5

Molecular Formula

C17H19MgN3O3S

Molecular Weight

369.72 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

600°C at 760 mmHg

SMILES

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CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[Mg+2]

InChI

InChI=1S/C17H19N3O3S.Mg/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3,(H,19,20);

InChIKey

MQEUGMWHWPYFDD-UHFFFAOYSA-N

LogP

2.5189400000000006

Topological Polar Surface Area

77.10000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

453

Synonyms & References

English

Omeprazole Magnesium
(S)-omeprazole magnesium
4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoicacidmethylest
Brevibloc
EsMolol Hcl API
Esmolol Hydrochloride (100 mg)
EsmololHclC16H25No4Hcl
Methyl 3-[4-(2-hydroxy-3-propan-2-ylamino-propoxy)phenyl]propanoate hydrochloride
methyl 3-[4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl]propionate Hydrochloride
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole magnesium salt (2:1)
Prilosec OTC
MAGNESIUM, BIS(6-METHOXY-2-(((4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL)SULFINYL-kappaO)-1H-BENZIMIDAZOLATO-kappaN3)-, (T-4)-
MLS001165732
CHEBI:94401
OMEPRAZOLE MAGNESIUM [MART.]
OMEPRAZOLE MAGNESIUM (USP IMPURITY)
MAGNESIUM, BIS(6-METHOXY-2-(((4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL)SULFINYL-.KAPPA.O)-1H-BENZIMIDAZOLATO-.KAPPA.N3)-, (T-4)-
SMR000550477
HMS2878H13
Esomeprazole magnesium
OMEPRAZOLE MAGNESIUM [USP IMPURITY]
UNII-426QFE7XLK
OMEPRAZOLE MAGNESIUM [USP MONOGRAPH]
magnesium(2+) bis(5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-2H-1,3-benzodiazol-2-ide)
DTXCID501477706
magnesium(2+) bis(5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-5H-1,3-benzodiazol-5-ide)
MFCD06798050
A810316
OMEPRAZOLE MAGNESIUM [VANDF]
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole, magnesium salt (2:1)
Omeprazole magnesium [USAN:USP]

MDL Number

MFCD11226784

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Omeprazole Magnesium (CAS: 95382-33-5)?

Omeprazole Magnesium (CAS: 95382-33-5) is a crystalline compound with a molecular weight of approximately 353.39 g/mol. It has a high solubility in water and is slightly acidic. Chemically, it is relatively stable but can react with strong bases. It is used in pharmaceutical formulations and has a pKa of about 5.0.

How is Omeprazole Magnesium (CAS: 95382-33-5) typically synthesized?

Omeprazole Magnesium is typically synthesized through a multistep process involving the transformation of 4-(trifluoromethyl)pyridine and substituted sulfonamides. The synthesis involves several key steps, including acylation, methylation, and cyclization. The reaction is usually catalyzed by titanium tetrachloride or similar Lewis acids with good yields and selectivity.

What industries use Omeprazole Magnesium (CAS: 95382-33-5)?

Omeprazole Magnesium (CAS: 95382-33-5) is primarily used in the pharmaceutical industry. It is a key ingredient in proton pump inhibitors (PPIs) used to treat conditions such as peptic ulcer disease, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. It is also used in veterinary medicine for similar conditions.

What precautions should be taken when handling Omeprazole Magnesium (CAS: 95382-33-5)?

When handling Omeprazole Magnesium (CAS: 95382-33-5), it is important to wear appropriate personal protective equipment (PPE), including gloves and goggles. Work should be conducted in a well-ventilated area or fume hood. In case of a spill, it should be cleaned up immediately using the appropriate absorbent material. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.