Compound Q&A

How is Omeprazole Magnesium (CAS: 95382-33-5) typically synthesized?

Answer

Omeprazole Magnesium
Omeprazole Magnesium is typically synthesized through a multistep process involving the transformation of 4-(trifluoromethyl)pyridine and substituted sulfonamides. The synthesis involves several key steps, including acylation, methylation, and cyclization. The reaction is usually catalyzed by titanium tetrachloride or similar Lewis acids with good yields and selectivity.

About

CAS No 95382-33-5
English Name Omeprazole Magnesium
Molecular Formula C17H19MgN3O3S
Molecular Weight 369.7211 g/mol
SMILES CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[Mg+2]
InChIKey MQEUGMWHWPYFDD-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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