Deoxyuridine | CAS No. 951-78-0

Deoxyuridine

Basic Information

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CAS Number

951-78-0

Molecular Formula

C9H12N2O5

Molecular Weight

228.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

164.0 to 168.0 deg-C

Boiling Point

370.01°C (rough estimate)

Density

1.3705 (rough estimate)

Water Solubility

300 g/L (20 ºC)

Flash Point

No data available

Refractive Index

52 ° (C=1, 1mol/L NaOH)

Specific Rotation

D22 +50° (c = 1.1 in N NaOH)

SMILES

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C1C(C(OC1N2C=CC(=O)NC2=O)CO)O

InChI

InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1

InChIKey

MXHRCPNRJAMMIM-SHYZEUOFSA-N

LogP

-1.8226999999999998

Topological Polar Surface Area

104.55000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

343

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
2-Deoxyuridine
Deoxyuridine
2'-Deoxyuridine
1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-furan-2-yl)pyrimidine-2,4(1H,3H)-dione
2`-Deoxyuridine
2’-Deoxyuridine
2'-Deoxyuridine-1’-d
[131I]-Deoxyuridine
[3H]-Deoxyuridine
1-(2-Deoxy-β-D-ribofuranosyl)uracil
2'-DEOXYTHYMIDINE-5'-DIPHOSPHATE TRISODIUM SALT
2'-deoxy-uridin
2'-dU
Deoxy-uridin
DEOXYURIDINE-2'
durd
Uracildeoxyr
Uracil deoxyriboside
1-(2-Deoxy-b-D-erythro-pentofuranosyl)uracil
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-b-D-erythro-pentofuranosyl)-
2,4(1H,3H)-Pyrimidinedione,1-(2-deoxy-b-D-ribofuranosyl)-
2'-Desoxyuridine
Deoxyribose uracil
NSC 23615
Uracildeoxyriboside
2′-dU
Uridine, 2'-deoxy-
1-(2-Deoxy-beta-D-ribofuranosyl)uracil
W78I7AY22C
2 -Deoxyuridine

MDL Number

MFCD00006527

Customs Code

29349990

FAQ

What is Deoxyuridine (CAS: 951-78-0)?

Deoxyuridine (CAS: 951-78-0) is a nucleoside compound composed of the sugar deoxyribose linked to the nucleobase uracil. Its chemical formula is C9H13N2O5, and it is a key component in DNA synthesis. Deoxyuridine is a white crystalline solid, soluble in water, and exhibits stability under standard conditions. It is commonly used as a research reagent and precursor in biochemical applications.

What are the main uses of Deoxyuridine (CAS: 951-78-0)?

Deoxyuridine (CAS: 951-78-0) is primarily utilized in pharmaceutical research for antiviral and antitumor drug development. It serves as a building block in nucleotide synthesis and is employed in DNA sequencing and genetic engineering. Additionally, it finds applications in industrial processes for nucleic acid-based products and as a nutritional supplement in certain formulations. Its role in biochemical studies makes it essential for molecular research.

Is Deoxyuridine (CAS: 951-78-0) safe?

Deoxyuridine (CAS: 951-78-0) is generally considered safe when handled properly in controlled environments. However, it may cause mild skin or eye irritation upon contact. Safety guidelines recommend using personal protective equipment (PPE) like gloves and safety goggles. It is not classified as hazardous under standard OSHA or EPA regulations but should be avoided in high concentrations to ensure optimal safety.

How should Deoxyuridine (CAS: 951-78-0) be stored?

Deoxyuridine (CAS: 951-78-0) should be stored in a cool, dry place, away from light, in airtight containers. Maintain storage temperature between 2-8°C and humidity levels below 60% to preserve stability. Avoid exposure to moisture and heat to prevent degradation. Ensure proper ventilation when handling to minimize inhalation risks, and store in a secure location to prevent accidental spills or contamination.