Bicyclo[2.2.1]hept-5-ene-2-carboxamide

Basic Information

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CAS Number

95-17-0

Molecular Formula

C8H11NO

Molecular Weight

137.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

188°C

Boiling Point

309.2 °C at 760 mmHg

Density

1.173

Flash Point

140.8 °C

Refractive Index

1.564

SMILES

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C1C2CC(C1C=C2)C(=O)N

InChI

InChI=1S/C8H11NO/c9-8(10)7-4-5-1-2-6(7)3-5/h1-2,5-7H,3-4H2,(H2,9,10)

InChIKey

ZTUUVDYQBLRAAC-UHFFFAOYSA-N

LogP

0.6839000000000001

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

197

Synonyms & References

English

Bicyclo[2.2.1]hept-5-ene-2-carboxamide
Bicyclo[2.2.1]-5-heptene-2-carboxamide
5-Norbornene-2-carboxamide (mixture of isomers)
5-NORBORNENE-2-CARBOXAMIDE
Bicyclo[2.2.1]hept-5-ene-2-carboxamide (mixture of isomers)
Human Granzyme B ELISA development kit (HRP)
2-Norbornene-5-exo-carboxamide
2-Norbornene-5-endo-carboxamide
Bicyclo(2.2.1)-5-heptene-2-carboxamide
bicyclo[2.2.1]hept-2-ene-5-carboxamide
Bicyclo[2.2.1]hept-5-ene-2-carboxamide, exo-
Bicyclo[2.2.1]hept-5-ene-2-carboxamide, endo-
Bicyclo(2.2.1)hept-5-ene-2-carboxamide, exo-
Bicyclo(2.2.1)hept-5-ene-2-carboxamide, endo-
Enamine_005891
NCIOpen2_001500
5-Norbornene-2-carboxamide (6CI, 7CI, 8CI)
5-Norbornene-2-carboxamide
DTXSID00915185
ZTUUVDYQBLRAAC-UHFFFAOYSA-N
DB-029187
J-802155
Bicyclo[2.2.1]hept-5-ene-2-carboxamide #
51757-85-8
N0911
95-17-0
AKOS016042456
4-09-00-00225 (Beilstein Handbook Reference)
CS-0159385
MFCD00187896
NSC92361

MDL Number

MFCD00187896

Customs Code

2924299090

FAQ

What are the physical and chemical properties of Bicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS: 95-17-0)?

Bicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS: 95-17-0) is a white crystalline solid with a molecular weight of approximately 142.21 g/mol. It has a low water solubility of 0.1 g/L at 25°C. The compound is moderately reactive and susceptible to hydrolysis under basic conditions. It has a characteristic amide functionality that makes it prone to nucleophilic attack.

How is Bicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS: 95-17-0) typically synthesized?

Bicyclo[2.2.1]hept-5-ene-2-carboxamide is typically synthesized by the condensation of 1-heptene-5-one with an amine. This reaction is usually carried out in the presence of a suitable base such as sodium hydride or potassium hydroxide, yielding a high selectivity and good yield. The exact reaction conditions can vary, but a temperature between 0-10°C is often used to minimize side reactions.

What industries use Bicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS: 95-17-0)?

Bicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS: 95-17-0) finds applications in the pharmaceutical industry, particularly in the synthesis of certain pharmaceutical intermediates. It is also used in the polymer industry for the development of specific polymer additives. Additionally, it has potential uses in the sensor and semiconductor industries as a precursor or component in various formulations.

What precautions should be taken when handling Bicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS: 95-17-0)?

When handling Bicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS: 95-17-0), appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats should be worn. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation exposure. In case of a spill, it should be carefully cleaned up using absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.