Bicyclo[2.2.1]hept-5-ene-2-carboxamide(CAS: 95-17-0)

Bicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS: 95-17-0) is a white crystalline solid with a molecular weight of approximately 142.21 g/mol. It has a low water solubility of 0.1 g/L at 25°C. The compound is moderately reactive and susceptible to hydrolysis under basic conditions. It has a characteristic amide functionality that makes it prone to nucleophilic attack.

Bicyclo[2.2.1]hept-5-ene-2-carboxamide is typically synthesized by the condensation of 1-heptene-5-one with an amine. This reaction is usually carried out in the presence of a suitable base such as sodium hydride or potassium hydroxide, yielding a high selectivity and good yield. The exact reaction conditions can vary, but a temperature between 0-10°C is often used to minimize side reactions.

Bicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS: 95-17-0) finds applications in the pharmaceutical industry, particularly in the synthesis of certain pharmaceutical intermediates. It is also used in the polymer industry for the development of specific polymer additives. Additionally, it has potential uses in the sensor and semiconductor industries as a precursor or component in various formulations.

When handling Bicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS: 95-17-0), appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats should be worn. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation exposure. In case of a spill, it should be carefully cleaned up using absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.