2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide

Basic Information

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CAS Number

947914-18-3

Molecular Formula

C22H20N2O3

Molecular Weight

360.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Density

1.253±0.06 g/cm3 (20 ºC 760 Torr),

Solubility

Insuluble (1.7E-4 g/L) (25 ºC),

SMILES

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CC1=CC(=CC=C1)C(=O)NC2=CC(=CC=C2)NC(=O)C3=CC=CC=C3OC

InChI

InChI=1S/C22H20N2O3/c1-15-7-5-8-16(13-15)21(25)23-17-9-6-10-18(14-17)24-22(26)19-11-3-4-12-20(19)27-2/h3-14H,1-2H3,(H,23,25)(H,24,26)

InChIKey

UTAJHKSGYJSZBR-UHFFFAOYSA-N

LogP

4.508220000000002

Topological Polar Surface Area

67.43 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

510

Synonyms & References

English

ML 365
ML-365
ML365
2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide
2-methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]benzamide
2-Methoxy-N-{3-[(3-methylbenzoyl)amino]phenyl}benzamide
MLS004829579
HMS3741G09
KUC108596N
BCP17056
BDBM50312105
s6554
SMR003532024
B8017
2-Methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]benzamide (ACI)
2-Methoxy-N-[3-(3-methylbenzamido)phenyl]benzamide
AC-36093
KUC108596N-02
HY-12345
KSC-19-198
KSC-396-044-1-P2
GLXC-04208
MFCD09204310
CS-3355
ML365?
947914-18-3
BS-51633
2-methoxy-N-[3-(3-methylbenzamido)phenyl]benzamide
EX-A1075
XMB91418
J-690405

MDL Number

MFCD09204310

FAQ

What are the physical and chemical properties of 2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide (CAS: 947914-18-3)?

2-Methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide is a white or off-white crystalline solid with a molecular weight of approximately 414.44 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethyl acetate. The compound is stable under normal conditions but may react with strong acids or bases. It does not possess significant reactivity under typical laboratory conditions but should be handled with care due to potential degradation over extended periods.

How is 2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide (CAS: 947914-18-3) typically synthesized?

2-Methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide can be synthesized via a multi-step process involving amide coupling. The synthesis typically begins with the formation of the 3-(3-methylbenzamido)phenyl group via an azide reduction and amidation reaction. Then, this group is coupled with 2-methoxybenzoyl chloride using a suitable coupling agent like HATU in the presence of a base such as DIPEA. The overall process is known for its high selectivity and yield, making it a reliable method for producing this compound.

What industries use 2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide (CAS: 947914-18-3)?

2-Methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide finds applications in the pharmaceutical industry, where it serves as an intermediate in the synthesis of drugs. It is also used in the polymer industry for the development of functionalized polymers with specific properties. Additionally, it may be utilized in the sensor industry for its ability to act as a molecular recognition element, and in the semiconductor industry for its potential use in organic electronics.

What precautions should be taken when handling 2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide (CAS: 947914-18-3)?

When handling 2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide, it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and sources of heat. In the event of a spill, it should be cleaned up carefully using appropriate solvent and disinfected. Always refer to the Material Safety Data Sheet (MSDS) for specific safety guidelines and emergency procedures.