Compound Q&A

How is 2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide (CAS: 947914-18-3) typically synthesized?

Answer

2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide
2-Methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide can be synthesized via a multi-step process involving amide coupling. The synthesis typically begins with the formation of the 3-(3-methylbenzamido)phenyl group via an azide reduction and amidation reaction. Then, this group is coupled with 2-methoxybenzoyl chloride using a suitable coupling agent like HATU in the presence of a base such as DIPEA. The overall process is known for its high selectivity and yield, making it a reliable method for producing this compound.

About

English Name 2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide
Molecular Formula C22H20N2O3
Molecular Weight 360.4130000000001 g/mol
SMILES CC1=CC(=CC=C1)C(=O)NC2=CC(=CC=C2)NC(=O)C3=CC=CC=C3OC
InChIKey UTAJHKSGYJSZBR-UHFFFAOYSA-N
Last Updated: 2025-11-04 22:31

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