2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine | CAS No. 94767-47-2

2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine

Basic Information

CAS Number

94767-47-2

Molecular Formula

C8H4F4O2

Molecular Weight

208.11 g/mol

AD

Basic Physical Properties

Refractive Index

1.4206

C1=CC=C2C(=C1)OC(C(O2)(F)F)(F)F

InChI

InChI=1S/C8H4F4O2/c9-7(10)8(11,12)14-6-4-2-1-3-5(6)13-7/h1-4H

InChIKey

QLCDBPBUHSKXHY-UHFFFAOYSA-N

LogP

2.6433999999999997

Topological Polar Surface Area

18.46 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

207

Safety Information

View Safety Information

Hazard Statement

Synonyms & References

English

  • EN300-6731457
  • 2,2,3,3-tetrafluoro-1,4-benzodioxene
  • 2,2,3,3-Tetrafluoro-1,4-benzodioxene;2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxine
  • E72291
  • 2,2,3,3-tetrafluoro-1,4-benzodioxan
  • 2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxine
  • SCHEMBL848935
  • 2,2,3,3-tetrafluoro-1,4-benzodioxine
  • 2,2,3,3-tetrafluorobenzo-1,4-dioxane
  • 94767-47-2
  • 1,4-Benzodioxin,2,2,3,3-tetrafluoro-2,3-dihydro-
  • FT-0609075
  • 2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxine
  • 2,2,3,3-Tetrafluorobenzodioxane
  • DTXSID30380206
  • CS-0257462
  • AKOS024318903
  • 2,2,3,3-Tetrafluoro-2,3-dihydro-benzo[1,4]dioxine
  • 2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxin
  • PS-11342
  • 2,2,3,3-tetrafluoro-1,4-benzodioxane
  • 2,2,3,3-tetrafluorobenzodioxene
  • MFCD00236308
  • SY333311
  • 2,2,3,3-Tetrafluoro-1,4-benzodioxane
  • 1,2-[(Tetrafluoroethylene)dioxy]benzene
  • 2,2,3,3-TETRAFLUOROBENZO-1,4-DIOXANE

MDL Number

MFCD00236308

FAQ

What are the physical and chemical properties of 2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine (CAS: 94767-47-2)?

2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine (CAS: 94767-47-2) is a colorless solid with a molecular weight of approximately 256.03 g/mol. It has a melting point of 85-86°C and is slightly soluble in water. It is chemically stable but reacts with strong bases. It is insoluble in water but soluble in common organic solvents like acetonitrile and dichloromethane.

How is 2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine (CAS: 94767-47-2) typically synthesized?

2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine (CAS: 94767-47-2) is synthesized using fluoroalkylation of 1,4-benzodioxane with trifluoroacetic anhydride under anhydrous conditions. The reaction involves the use of a base such as potassium tert-butoxide and typically yields 90% purity with good selectivity. This method ensures the formation of the desired product with minimal by-products.

What industries use 2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine (CAS: 94767-47-2)?

2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine (CAS: 94767-47-2) is used in the pharmaceutical industry for the synthesis of various drug candidates. It is also utilized in the polymer industry for the development of special polymers with enhanced properties. Additionally, it finds applications in the semiconductor and sensor industries due to its unique chemical and physical properties.

What precautions should be taken when handling 2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine (CAS: 94767-47-2)?

When handling 2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine (CAS: 94767-47-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated environment or a fume hood. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed safety information and guidelines.

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