Compound Q&A

How is 2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine (CAS: 94767-47-2) typically synthesized?

Answer

2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine
2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine (CAS: 94767-47-2) is synthesized using fluoroalkylation of 1,4-benzodioxane with trifluoroacetic anhydride under anhydrous conditions. The reaction involves the use of a base such as potassium tert-butoxide and typically yields 90% purity with good selectivity. This method ensures the formation of the desired product with minimal by-products.

About

CAS No 94767-47-2
English Name 2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxine
Molecular Formula C8H4F4O2
Molecular Weight 208.11 g/mol
SMILES C1=CC=C2C(=C1)OC(C(O2)(F)F)(F)F
InChIKey QLCDBPBUHSKXHY-UHFFFAOYSA-N
Last Updated: 2026-03-17 01:51

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