2-[(Trimethylsilyl)ethynyl]-3-pyridinamine | CAS No. 947330-64-5
2-[(Trimethylsilyl)ethynyl]-3-pyridinamine
Basic Information
CAS Number
947330-64-5
Molecular Formula
C10H14N2Si
Molecular Weight
108.14 g/mol
AD
Basic Physical Properties
Safety Information
View Safety InformationHazard Class
Class IRRITANT
Class IRRITANT
Synonyms & References
English
- 2-[2-(trimethylsilyl)ethynyl]pyridin-3-amine
- 2-(2-trimethylsilylethynyl)pyridin-3-amine
- AS-65668
- SCHEMBL5925876
- CS-0364195
- 2-((Trimethylsilyl)ethynyl)pyridin-3-amine
- 2-(Trimethylsilylethynyl)pyridin-3-amine
- MFCD12922741
- 2-((Trimethylsilyl)ethynyl)pyridin-3-amine, AldrichCPR
- AKOS006337026
- 947330-64-5
MDL Number
MFCD12922741
FAQ
What are the physical and chemical properties of 2-[(Trimethylsilyl)ethynyl]-3-pyridinamine (CAS: 947330-64-5)?
2-[(Trimethylsilyl)ethynyl]-3-pyridinamine (CAS: 947330-64-5) is a crystalline solid with a molecular weight of approximately 263.4 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetonitrile. The compound exhibits limited reactivity, primarily through the silyl ethynylation moiety, which can undergo substitution reactions under certain conditions.
How is 2-[(Trimethylsilyl)ethynyl]-3-pyridinamine (CAS: 947330-64-5) typically synthesized?
2-[(Trimethylsilyl)ethynyl]-3-pyridinamine (CAS: 947330-64-5) can be synthesized through a multi-step process starting from pyridine and silyl ethynyl chloride. The key steps include alkyne coupling reactions and amination, often catalyzed by a palladium complex. The overall yield is around 70-80%, with good selectivity for the desired amine product.
What industries use 2-[(Trimethylsilyl)ethynyl]-3-pyridinamine (CAS: 947330-64-5)?
2-[(Trimethylsilyl)ethynyl]-3-pyridinamine (CAS: 947330-64-5) is primarily used in pharmaceuticals for the synthesis of intermediate compounds. It also has applications in the development of novel materials, such as polymers and sensors, due to its unique chemical properties.
What precautions should be taken when handling 2-[(Trimethylsilyl)ethynyl]-3-pyridinamine (CAS: 947330-64-5)?
When handling 2-[(Trimethylsilyl)ethynyl]-3-pyridinamine (CAS: 947330-64-5), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Store the compound in a well-ventilated area and avoid inhalation of dust or vapors. In case of a spill, use appropriate absorbent materials and follow the safety data sheet (SDS) for disposal instructions. Always work in a fume hood to minimize exposure and follow all standard laboratory safety procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
![2-[(Trimethylsilyl)ethynyl]-3-pyridinamine — JiErShengHua （ ShangHai ） Co Ltd](https://static.chemtradehub.com/suppliers/67cecb182b2de6e8e95a5951/67cecb182b2de6e8e95a5951-logo.webp){kind=logo}
![2-[(Trimethylsilyl)ethynyl]-3-pyridinamine — MoXiMaiMoTaPu Biotechnology Co Ltd](https://static.chemtradehub.com/suppliers/67cece612b2de6e8e95a619b/67cece612b2de6e8e95a619b-logo.webp){kind=logo}
![2-[(Trimethylsilyl)ethynyl]-3-pyridinamine — JiangSuAiKangShengWuYiYaoYanFa Co Ltd](https://static.chemtradehub.com/suppliers/67cec9452b2de6e8e95a52fa/67cec9452b2de6e8e95a52fa-logo.webp){kind=logo}
![2-[(Trimethylsilyl)ethynyl]-3-pyridinamine — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}