(1,4-Dibenzyl-2-piperazinyl)methanol

Basic Information

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CAS Number

94437-04-4

Molecular Formula

C19H24N2O

Molecular Weight

296.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C1CN(C(CN1CC2=CC=CC=C2)CO)CC3=CC=CC=C3

InChI

InChI=1S/C19H24N2O/c22-16-19-15-20(13-17-7-3-1-4-8-17)11-12-21(19)14-18-9-5-2-6-10-18/h1-10,19,22H,11-16H2

InChIKey

SOUPGWGAPDMYFM-UHFFFAOYSA-N

LogP

2.3653000000000004

Topological Polar Surface Area

26.71 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

311

Synonyms & References

English

(+)-1,4-Bis(benzyl)-2-piperazinemethanol
1,4-dibenzyl-2-hydroxymethylpiperazine
(1,4-dibenzyl-piperaziN-2-yl)methanol
(1,4-dibenzyl-piperazin-2-yl)-methanol
(1,4-dibenzylpiperazin-2-yl)-methanol
FT-0753773
2-hydroxymethyl-1,4-di-phenylmethyl piperazine
94437-04-4
1,4-dibenzyl-2-(hydroxymethyl)piperazine
[1,4-bis(phenylmethyl)-2-piperazinyl]methanol
SOUPGWGAPDMYFM-UHFFFAOYSA-N
1,4-bis(phenylmethyl)-2-piperazinemethanol
(1,4-dibenzylpiperazin-2-yl)methanol
DTXSID00445513
AB6957
(1 pound not4-Dibenzyl-piperazin-2-yl)-methanol
J-500031
(RS)-1,4-Bis(phenylmethyl)-2-piperazinemethanol
AKOS022171802
SCHEMBL65364
MFCD01318335
1,4-bis(phenylmethyl)2-piperazinemethanol
AS-44811
(1,4-Dibenzylpiperazin-2-yl)methanol
2-Piperazinemethanol, 1,4-bis(phenylmethyl)-

MDL Number

MFCD01318335

FAQ

What are the physical and chemical properties of (1,4-Dibenzyl-2-piperazinyl)methanol (CAS: 94437-04-4)?

(1,4-Dibenzyl-2-piperazinyl)methanol is a white crystalline solid with a molecular weight of approximately 388.4 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and acetone. Chemically, it is stable but reacts with strong acids and bases. It has a pKa of about 8.5. Its solubility is important for its use in various applications, including pharmaceuticals and sensors.

How is (1,4-Dibenzyl-2-piperazinyl)methanol (CAS: 94437-04-4) typically synthesized?

(1,4-Dibenzyl-2-piperazinyl)methanol is commonly synthesized via the reaction of 2-piperazinecarboxylic acid and benzyl bromide. The reaction is catalyzed by a phase transfer catalyst, and the product is obtained with good yield. The process is typically carried out in an organic solvent like dichloromethane under mild conditions, ensuring high purity and selectivity.

What industries use (1,4-Dibenzyl-2-piperazinyl)methanol (CAS: 94437-04-4)?

(1,4-Dibenzyl-2-piperazinyl)methanol finds applications in various industries. In pharmaceuticals, it is used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). It is also employed in the manufacturing of sensors and electronic devices due to its unique physicochemical properties. Additionally, it has potential uses in the polymer industry for developing novel materials.

What precautions should be taken when handling (1,4-Dibenzyl-2-piperazinyl)methanol (CAS: 94437-04-4)?

When handling (1,4-Dibenzyl-2-piperazinyl)methanol, it is essential to follow proper laboratory safety protocols. Wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work in a well-ventilated area or a fume hood to minimize inhalation risks. In case of a spill, neutralize the substance with an appropriate neutralizing agent and dispose of it according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.